There is an important reason why ‘genomic instability’ takes the number one position on the list of hallmarks. It is often called the big boss of the 4 primary hallmarks. Ultimately, genomic instability influences every single parameter, process and outcome of all the other hallmarks. The blueprint (or code) printed in our genome is the information for all life and is the starting point of everything that makes us human.
This is now becoming more and more the focus of longevity science around the world. New research techniques, new money , new theories, all excited by the discoveries that our cellular performance, our genetic code, our DNA function can all be protected and repaired to potentially operate indefinitely.
July was an exciting month in the scientific world of anti-ageing and longevity. A new discovery! A new understanding! Another step towards finding new disease treatments and novel medicines that could vastly improve our healthspan and lifespan.
DNA is the recipe for all life on Earth, by coding for proteins that the entire organism is made of. Our bodies have complex systems in place that make sure our DNA is organised properly and that each new cell gets a complete and unchanged copy. If the complex system involved in copying DNA fails, or if bad things are present in the environment, a mistake in the sequence of DNA can occur. These mistakes, called mutations, can happen at any phase of life, beginning with a growing baby’s first cells all the way to an adult’s mature cells.
Mitochondria are the powerhouse of the cell. They are the part of the cell responsible for turning the food into energy for the body. Mitochondrial dysfunction is linked to a number of diseases. In this article you'll learn all you need to know about the mitochondria, how they work, and how they can affect your health.
The Hydra, a small freshwater invertebrate, is an advantageous model organism for regenerative biologists. Named after the serpent from Greek mythology that grew two new heads for each one cut off, this tiny, jellyfish-like creature holds within its genomic code the key to biological immortality.
Hydra are unique because their stem cells exist in a continuous state of renewal. Kept safe and in isolation, these organisms show no signs of aging. Outside the lab, the only real threats they face are predators, weather extremes and disease.